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estradiol 17-dihydrotrigonelline

Names

[ CAS No. ]:
103562-82-9

[ Name ]:
estradiol 17-dihydrotrigonelline

[Synonym ]:
3-hydroxy-17β-<<(1-methyl-1,4-dihydropyridin-3-yl)carbonyl>oxy>estra-1,3,5(10)-triene
17β-[(1-methyl-1,4-dihydro-3-pyridinyl)carbonyloxy]estra-1,3,5(10)-trien-3-ol
estra-1,3,5(10)-triene-3,17β-diol-17-(1,4-dihydro-1-methylpyridine-3-carboxylate)
3-hydroxy-17β-{[(1-methyl-1,4-dihydropyridin-3-yl)carbonyl]oxy}estra-1,3,5(10)-triene
3-hydroxy-17β-<<(1-methyl-1,4-dihydropyridin-3-yl)-carbonyl>-oxy>estra-1,3,5(10)-triene
17β-[(1-Methyl-1,4-dihydro-3-pyridinyl)carbonyloxy]estra-1,3,5(10)-trien-3-ol
1-Methyl-1,4-dihydro-pyridine-3-carboxylic acid (8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl ester

Biological Activity

[Description]:

E2-CDS (Estradiol 17-Dihydrotrigonelline) is a redox-based chemical delivery system for estradiol (E2). E2-CDS is capable of sustained and brain-selective delivery of estradiol[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. G Mullersman, et al.  High-performance liquid chromatographic assay of a central nervous system (CNS)-directed estradiol chemical delivery system and its application after intravenous administration to rats. Pharm Res. 1988 Mar;5(3):172-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C25H31NO3

[ Molecular Weight ]:
393.51900

[ Exact Mass ]:
393.23000

[ PSA ]:
49.77000

[ LogP ]:
4.83110

Related Compounds