H-Gly-Arg-pNA · 2 HCl

Names

[ Name ]:
H-Gly-Arg-pNA · 2 HCl

[Synonym ]:
Glycyl-N-(4-nitrophenyl)-L-argininamide
L-Argininamide, glycyl-N-(4-nitrophenyl)-

Biological Activity

[Description]:

Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal [1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Hutchinson DW, et, al. The preparation and properties of immobilised dipeptidyl-aminopeptidase I (cathepsin C). Biochim Biophys Acta. 1987 Nov 5;916(1):1-4.

[2]. Potempa J, et, al. Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis. J Biol Chem. 1998 Aug 21;273(34):21648-57.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₁₄H₂₁N₇O₄

[ Molecular Weight ]:
351.36

[ Exact Mass ]:
351.165497

[ LogP ]:
-0.67

[ Index of Refraction ]:
1.664

Related Compounds

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