5-Methyl-1H-indole-2-carboxylic acid
Names
[ CAS No. ]:
10241-97-1
[ Name ]:
5-Methyl-1H-indole-2-carboxylic acid
[Synonym ]:
5-Methyl-1H-indole-2-carboxylic acid
MFCD00047166
1H-Indole-2-carboxylic acid, 5-methyl-
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
421.2±25.0 °C at 760 mmHg
[ Melting Point ]:
236-238°C (dec.)
[ Molecular Formula ]:
C10H9NO2
[ Molecular Weight ]:
175.184
[ Flash Point ]:
208.5±23.2 °C
[ Exact Mass ]:
175.063324
[ PSA ]:
53.09000
[ LogP ]:
2.77
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.696
MSDS
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Med. Chem. 46 , 3957-3960, (2003)
Following the discovery of the human histamine H4 receptor, a high throughput screen of our corporate compound collection identified compound 6 as a potential lead. Investigation of the SAR resulted i...
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolutionBioorg. Med. Chem. Lett. 20 , 6483, (2010)
Structure-guided techniques were used to evolve a 5-pyridinyl pyrazole-3-carboxylate fragment into a series of 5-aryl-carbamoyl-3-phenyl-imidazole-4-carboxylates, examples of which inhibited the Pin1 ...