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Triclosan D3

Names

[ CAS No. ]:
1020719-98-5

[ Name ]:
Triclosan D3

[Synonym ]:
2'-Hydroxy-2,4,4'-trichlorodiphenyl-d3 Ether
Gamophen-d3
5-Chloro-2-(2,4-dichloro-3,5,6-d3-phenoxy)phenol-d3
Irgasan DP 300-d3
2,4,4'-Trichloro-2'-hydroxydiphenyl-d3 Ether
Triclosan-d3
Aquasept-d3

Biological Activity

[Description]:

Triclosan D3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal
Signaling Pathways >> Autophagy >> Autophagy
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Weatherly LM, et al. Triclosan exposure, transformation, and human health effects. J Toxicol Environ Health B Crit Rev. 2017;20(8):447-469.

[3]. Ley C, et al. Triclosan and triclocarban exposure and thyroid function during pregnancy-A randomized intervention. Reprod Toxicol. 2017 Dec;74:143-149.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H7Cl3O2

[ Molecular Weight ]:
289.54200

[ Exact Mass ]:
287.95100

[ PSA ]:
29.46000

[ LogP ]:
5.14470

Related Compounds