Sappanone A

Names

[ CAS No. ]:
102067-84-5

[ Name ]:
Sappanone A

[Synonym ]:
3-(3,4-Dihydroxybenzylidene)-7-hydroxy-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 3-[(3,4-dihydroxyphenyl)methylene]-2,3-dihydro-7-hydroxy-

Biological Activity

[Description]:

Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2

Research Areas >> Inflammation/Immunology

[References]

[1]. Lee S, et, al. Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Int Immunopharmacol. 2015 Sep;28(1):328-36.

[2]. Liu X, et, al. Sappanone A Attenuates Allergic Airway Inflammation in Ovalbumin-Induced Asthma. Int Arch Allergy Immunol. 2016;170(3):180-6.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
605.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₂O₅

[ Molecular Weight ]:
284.263

[ Flash Point ]:
233.2±25.0 °C

[ Exact Mass ]:
284.068481

[ LogP ]:
2.49

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.754

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.