Tie-2 inhibitor 7

Names

[ CAS No. ]:
1020412-97-8

[ Name ]:
Tie-2 inhibitor 7

[Synonym ]:
Tie-2 Inhibitor 7

Biological Activity

[Description]:

Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[Target]

Tie2:1 μM (IC50)

Tie2:1.3 μM (IC50)

[References]

[1]. Jinqi Liu, et al. Identification and characterization of small-molecule inhibitors of Tie2 kinase. FEBS Lett. 2008 Mar 5;582(5):785-91.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₅N₃O₅

[ Molecular Weight ]:
529.63

[ Exact Mass ]:
523.21100

[ PSA ]:
108.83000

[ LogP ]:
6.02450

Tie-2 inhibitor 7

Names

Biological Activity

Chemical & Physical Properties

Related Compounds