Trenbolone

Names

[ Name ]:
Trenbolone

[Synonym ]:
4,9,11-Estratrien-17b-ol-3-one
Trienolone
17-β-Trenbolone
Estra-4,9,11-trien-3-one, 17-hydroxy-, (17-β)- (9CI)
MFCD00214395
17β-hydroxy-estra-4,9,11-trien-3-one
17b-Hydroxy-19-norandrosta-4,9,11-trien-3-one
19-Norandrosta-4,9,11-trien-17b-ol-3-one
Estra-4,9,11-trien-3-one, 17-hydroxy-, (17β)-
(17β)-17-Hydroxyestra-4,9,11-trien-3-one
Trenbolone

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
490.8±45.0 °C at 760 mmHg

[ Melting Point ]:
170°C

[ Molecular Formula ]:
C₁₈H₂₂O₂

[ Molecular Weight ]:
270.366

[ Flash Point ]:
208.2±21.3 °C

[ Exact Mass ]:
270.161987

[ PSA ]:
37.30000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.605

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7752000

CHEMICAL NAME :: Estra-4,9,11-trien-3-one, 17-beta-hydroxy-

CAS REGISTRY NUMBER :: 10161-33-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H22-O2

MOLECULAR WEIGHT :: 270.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Fibroblast

DOSE/DURATION :: 2500 ug/L

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 62,49,1988

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R60

[ Safety Phrases ]:
S53-S22-S36/37/39-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KG7752000

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2942000000

Articles

Evidence of small modulation of ethinylestradiol induced effects by concurrent exposure to trenbolone in male eelpout Zoarces viviparus

Environ. Pollut. 178 , 189-96, (2013)

The interaction of xenobiotics is common in aquatic ecosystems; therefore, we wanted to evaluate if trenbolone (TB) modulates the effects of 17α-ethinylestradiol (EE2). Male eelpout (Zoarces viviparus...

Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.

PLoS ONE 7 , e36069, (2012)

The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is...

17β-trenbolone, an anabolic-androgenic steroid as well as an environmental hormone, contributes to neurodegeneration.

Toxicol. Appl. Pharmacol. 282(1) , 68-76, (2015)

Both genetic and environmental factors contribute to neurodegenerative disorders. In a large number of neurodegenerative diseases (for example, Alzheimer's disease (AD)), patients do not carry the mut...