Policresulen

Names

[ Name ]:
Policresulen

[Synonym ]:
Policresuleno
FC1272
Policresulen
MFCD00869035
Policresulenum
Policresulene

Biological Activity

[Description]:

Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Wu DW, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015;36(9):1126-1136.

Chemical & Physical Properties

[ Density]:
1.631 g/cm3

[ Molecular Formula ]:
(C₇H₈O₄S_.CH₂O)x

[ Molecular Weight ]:
218.22700

[ Exact Mass ]:
218.02500

[ PSA ]:
100.05000

[ LogP ]:
2.47910

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2908999090

Customs

[ HS Code ]: 2908999090

[ Summary ]:
2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%