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Cetirizine Impurity B dihydrochloride

Names

[ CAS No. ]:
1000690-91-4

[ Name ]:
Cetirizine Impurity B dihydrochloride

Biological Activity

[Description]:

Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055-1080, 1993.

[2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5.

[3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H23Cl3N2O2

[ Molecular Weight ]:
417.76

Related Compounds