GSK-3β inhibitor 11

Modify Date: 2024-01-21 00:59:15

GSK-3β inhibitor 11 Structure
GSK-3β inhibitor 11 structure
Common Name GSK-3β inhibitor 11
CAS Number 536731-65-4 Molecular Weight 393.416
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C20H15N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK-3β inhibitor 11


GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research[1].

 Names

Name 2H-Isoindole-2-acetamide, 1,3-dihydro-N-[4-(3-methoxyphenyl)-2-thiazolyl]-1,3-dioxo-
Synonym More Synonyms

 GSK-3β inhibitor 11 Biological Activity

Description GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research[1].
Related Catalog
Target

GSK-3β:10.02 μM (IC50)

References

[1]. Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C20H15N3O4S
Molecular Weight 393.416
Exact Mass 393.078339
LogP 3.76
Index of Refraction 1.686
Storage condition -20°C

 Synonyms

2H-Isoindole-2-acetamide, 1,3-dihydro-N-[4-(3-methoxyphenyl)-2-thiazolyl]-1,3-dioxo-
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide