Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate

Modify Date: 2024-01-02 12:07:51

Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate Structure
Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate structure
Common Name Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate
CAS Number 20329-96-8 Molecular Weight 252.263
Density 1.1±0.1 g/cm3 Boiling Point 370.6±37.0 °C at 760 mmHg
Molecular Formula C13H16O5 Melting Point 91-92ºC
MSDS N/A Flash Point 163.5±26.5 °C

 Use of Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate


(E)-Methyl 3,4,5-trimethoxycinnamate is a bioactive natural phenylpropanoid. (E)-Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. (E)-Methyl 3,4,5-trimethoxycinnamate also has antiarrhythmic effect, leads to suppression of triggered activities in rabbit myocytes[1][2].

 Names

Name methyl 3,4,5-trimethoxycinnamate
Synonym More Synonyms

  Biological Activity

Description (E)-Methyl 3,4,5-trimethoxycinnamate is a bioactive natural phenylpropanoid. (E)-Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. (E)-Methyl 3,4,5-trimethoxycinnamate also has antiarrhythmic effect, leads to suppression of triggered activities in rabbit myocytes[1][2].
Related Catalog
References

[1]. Olajide OA, et al. Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. Inflammopharmacology. 2020 Oct;28(5):1315-1326.  

[2]. Zhao Z, et al. Potential antiarrhythmic effect of methyl 3,4,5-trimethoxycinnamate, a bioactive substance from roots of polygalae radix: suppression of triggered activities in rabbit myocytes. Biol Pharm Bull. 2013;36(2):238-44.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 370.6±37.0 °C at 760 mmHg
Melting Point 91-92ºC
Molecular Formula C13H16O5
Molecular Weight 252.263
Flash Point 163.5±26.5 °C
Exact Mass 252.099777
PSA 53.99000
LogP 1.77
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.529

 Safety Information

HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, methyl ester
Methyl (2E)-3-(3,4,5-trimethoxyphenyl)acrylate
methyl (2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate
Methyl 3,4,5-trimethoxycinnamate
2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, methyl ester, (2E)-
Methyl trans-3,4,5-trimethoxycinnamate
Methyl (E)-6,7,8-trimethoxycinnamate
3,4,5-trimethoxycinnamic acid methyl ester
Methyl 3,4,5-TriMethyl cinnaMate
Cinnamic acid, 3,4,5-trimethoxy-, methyl ester
Methyl 3,4,5-trimethoxy-trans-cinnamate