(-)-东莨菪碱氢溴酸盐结构式
|
常用名 | (-)-东莨菪碱氢溴酸盐 | 英文名 | Scopolamine hydrobromide trihydrate |
|---|---|---|---|---|
| CAS号 | 6533-68-2 | 分子量 | 438.311 | |
| 密度 | 1.31 g/cm3 | 沸点 | 460.3ºC at 760 mmHg | |
| 分子式 | C17H28BrNO7 | 熔点 | 197-194 °C | |
| MSDS | 中文版 美版 | 闪点 | 232.2ºC | |
| 符号 |
GHS06 |
信号词 | Danger |
(-)-东莨菪碱氢溴酸盐用途【用途一】 是一个支气管扩张剂，适用于慢性阻塞性肺疾病（COPD）的维持治疗，包括慢性支气管炎和肺气肿，伴随性呼吸困难的维持治疗及急性发作的预防。 |
| 中文名 | 氢溴酸菪胺 |
|---|---|
| 英文名 | (-)-Scopolamine hydrobromide trihydrate |
| 中文别名 | 氘代氢溴酸东莨菪碱-d3 | 氢溴酸东莨菪碱 | 氢溴酸东莨菪胺 | 东莨菪碱氢溴酸盐三水合物 |
| 英文别名 | 更多 |
| 密度 | 1.31 g/cm3 |
|---|---|
| 沸点 | 460.3ºC at 760 mmHg |
| 熔点 | 197-194 °C |
| 分子式 | C17H28BrNO7 |
| 分子量 | 438.311 |
| 闪点 | 232.2ºC |
| 精确质量 | 437.104919 |
| PSA | 89.99000 |
| LogP | 1.62120 |
| 外观性状 | 白色至灰白色粉末 |
| 折射率 | -25.5 ° (C=5, H2O) |
| 储存条件 | Poison room |
| 稳定性 | Stable, but air and light sensitive. Incompatible with acids, bases, strong oxidizing agents. Slightly hygroscopic. |
| 符号 |
GHS06 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H300-H310-H330 |
| 警示性声明 | P260-P264-P280-P284-P301 + P310-P302 + P350 |
| 个人防护装备 | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| 危害码 (欧洲) | T+: Very toxic; |
| 风险声明 (欧洲) | R26/27/28 |
| 安全声明 (欧洲) | S45-S25-S1 |
| 危险品运输编码 | UN1544 6.1/PG 3 |
| RTECS号 | YM4550000 |
| 危险类别 | 6.1 |
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Dry eye predisposes to corneal neovascularization and lymphangiogenesis after corneal injury in a murine model.
Cornea 33(6) , 621-7, (2014) Dry eye disease is becoming recognized as an immune-inflammation mediated disorder. Surgical insults such as corneal incision or suture can aggravate dry eye. We sought to determine whether underlying... |
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Pretreatment with 5-hydroxymethyl-2-furaldehyde blocks scopolamine-induced learning deficit in contextual and spatial memory in male mice.
Pharmacol. Biochem. Behav. 134 , 57-64, (2015) 5-Hydroxymethyl-2-furaldehyde (5-HMF) is a compound derived from the dehydration of certain sugars. The aim of the present study was to evaluate the effect of 5-HMF on the cognitive impairment induced... |
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Deer bone extract prevents against scopolamine-induced memory impairment in mice.
J. Med. Food 18(2) , 157-65, (2015) Deer bone has been used as a health-enhancing food as well as an antiaging agent in traditional Oriental medicine. Recently, the water extract of deer bone (DBE) showed a neuroprotective action agains... |
| EINECS 204-050-6 |
| Scopolamine hydrobromide |
| Benzeneacetic acid, α-(hydroxymethyl)-, (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0]non-7-yl ester, (αS)-, hydrobromide, hydrate (1:1:3) |
| (1S,2R,4S,5S,7R)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate hydrobromide trihydrate |
| MFCD00150066 |
| Scopolamine hydrobromide trihydrate |
| Hyoscine hydrobromide trihydrate |
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