盐酸哌甲酯结构式
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常用名 | 盐酸哌甲酯 | 英文名 | methylphenidate hydrochloride |
|---|---|---|---|---|
| CAS号 | 298-59-9 | 分子量 | 269.767 | |
| 密度 | N/A | 沸点 | 327.6ºC at 760 mmHg | |
| 分子式 | C14H20ClNO2 | 熔点 | 224 - 226ºC | |
| MSDS | 中文版 美版 | 闪点 | 152ºC | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
盐酸哌甲酯用途Methylphenidate hydrochloride is a central nervous system (CNS) stimulant, that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. |
| 中文名 | 盐酸哌甲酯 |
|---|---|
| 英文名 | methylphenidate hydrochloride |
| 中文别名 | alpha-苯基-2-哌啶乙酸甲酯盐酸盐 |
| 英文别名 | 更多 |
| 沸点 | 327.6ºC at 760 mmHg |
|---|---|
| 熔点 | 224 - 226ºC |
| 分子式 | C14H20ClNO2 |
| 分子量 | 269.767 |
| 闪点 | 152ºC |
| 精确质量 | 269.118256 |
| PSA | 38.33000 |
| LogP | 3.21610 |
| 外观性状 | 白色结晶粉末 |
| 蒸汽压 | 0.000199mmHg at 25°C |
| 折射率 | 1.523 |
| 储存条件 | Store at RT |
| 稳定性 | Stable. Combustible. Incompatible with strong oxidizing agents, alkalies, barbiturates. |
| 符号 |
GHS07, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H302-H334 |
| 警示性声明 | P261-P342 + P311 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| 危害码 (欧洲) | Xn: Harmful; |
| 风险声明 (欧洲) | R22;R42 |
| 安全声明 (欧洲) | 22-26-36 |
| 危险品运输编码 | UN 3249 |
| WGK德国 | 3 |
| RTECS号 | TM3850000 |
| 包装等级 | III |
| 危险类别 | 6.1(b) |
| 海关编码 | 2933399090 |
|
~58%
盐酸哌甲酯 298-59-9 |
| 文献：US2004/176412 A1, ; Page/Page column 5-6 ; |
| 盐酸哌甲酯上游产品 1 | |
|---|---|
| 盐酸哌甲酯下游产品 1 | |
| 海关编码 | 2933399090 |
|---|---|
| 中文概述 | 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期 |
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Alterations in brain neurotrophic and glial factors following early age chronic methylphenidate and cocaine administration.
Behav. Brain Res. 282 , 125-32, (2015) Attention deficit hyperactivity disorder (ADHD) overdiagnosis and a pharmacological attempt to increase cognitive performance, are the major causes for the frequent (ab)use of psychostimulants in non-... |
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Methylphenidate Increases Glutamate Uptake in Bergmann Glial Cells.
Neurochem. Res. 40 , 2317-24, (2015) Glutamate, the main excitatory transmitter in the vertebrate brain, exerts its actions through the activation of specific membrane receptors present in neurons and glial cells. Over-stimulation of glu... |
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Behavioral and neuronal recording of the nucleus accumbens in adolescent rats following acute and repetitive exposure to methylphenidate.
J. Neurophysiol. 113(1) , 369-79, (2015) The nucleus accumbens (NAc) has been shown to play a key role in the brain's response to methylphenidate (MPD). The present study focuses on neuronal recording from this structure. The study postulate... |
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