L-α-磷脂酰肌醇-4,5-双磷酸钠盐

• 常用名: L-α-磷脂酰肌醇-4,5-双磷酸钠盐
• 英文名: Phosphatidylinositol 4,5-bisphosphate
• CAS号: 245126-95-8
• 分子量: 1047.088
• 密度: 1.3±0.1 g/cm3
• 沸点: 1034.8±75.0 °C at 760 mmHg
• 分子式: C₄₇H₈₅O₁₉P₃
• 熔点: N/A
• 闪点: 579.6±37.1 °C

L-α-磷脂酰肌醇-4,5-双磷酸钠盐用途

磷脂酰肌醇4,5-二磷酸(L-α-磷脂酰肌醇-4,5-二磷酸)是细胞膜的磷脂成分,是磷脂酶C(PLC)和磷脂酰肌醇3-激酶(PI3K)的底物,也是主要信使[1][2][3]。

L-α-磷脂酰肌醇-4,5-双磷酸钠盐名称

• 中文名: L-α-磷脂酰肌醇-4,5-双磷酸钠盐
• 英文名: (2R)-1-[(Hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl)oxy]-3-(stearoyloxy)-2-propanyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate

L-α-磷脂酰肌醇-4,5-双磷酸钠盐生物活性

• 描述: 磷脂酰肌醇4,5-二磷酸(L-α-磷脂酰肌醇-4,5-二磷酸)是细胞膜的磷脂成分,是磷脂酶C(PLC)和磷脂酰肌醇3-激酶(PI3K)的底物,也是主要信使[1][2][3]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Katan M, et, al. Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane. Essays Biochem. 2020 Sep 23;64(3):513-531.

  [2]. Arreola J, et, al. Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate Cell Calcium. 2019 Dec;84:102103.

  [3]. Kato M, et, al. Arabidopsis PCaP2 modulates the phosphatidylinositol 4,5-bisphosphate signal on the plasma membrane and attenuates root hair elongation. Plant J. 2019 Aug;99(4):610-625.

L-α-磷脂酰肌醇-4,5-双磷酸钠盐物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 1034.8±75.0 °C at 760 mmHg
• 分子式: C₄₇H₈₅O₁₉P₃
• 分子量: 1047.088
• 闪点: 579.6±37.1 °C
• 精确质量: 1046.489746
• LogP: 13.22
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.538

L-α-磷脂酰肌醇-4,5-双磷酸钠盐英文别名

• (2R)-1-[(Hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl)oxy]-3-(stearoyloxy)-2-propanyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate
• 5,8,11,14-Eicosatetraenoic acid, (1R)-2-[[hydroxy[[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy]phosphinyl]oxy]-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester, (5Z,8Z,11Z,14Z)-