去甲右美沙芬酒石酸盐结构式
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常用名 | 去甲右美沙芬酒石酸盐 | 英文名 | Dextrorphan tartrate |
|---|---|---|---|---|
| CAS号 | 143-98-6 | 分子量 | 407.457 | |
| 密度 | N/A | 沸点 | 410.4ºC at 760 mmHg | |
| 分子式 | C21H29NO7 | 熔点 | 201-204°C | |
| MSDS | 中文版 美版 | 闪点 | 207.2ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
去甲右美沙芬酒石酸盐用途Dextrophan tartrate is a glutamate receptor antagonist potentially for the treatment of stroke. Dextrorphan (DXO) is a psychoactive drug of the morphinan chemical class which acts as an antitussive or cough suppressant and dissociative hallucinogen. It is the dextrorotatory-stereoisomer of racemorphan, the levo-half being levorphanol. Dextrorphan is produced by O-demethylation of dextromethorphan by CYP2D6. Dextrorphan is an NMDA antagonist and contributes to the psychoactive effects of dextromethorphan. |
| 中文名 | 去甲右美沙芬酒石酸盐 |
|---|---|
| 英文名 | Dextrorphan tartrate |
| 英文别名 | 更多 |
| 沸点 | 410.4ºC at 760 mmHg |
|---|---|
| 熔点 | 201-204°C |
| 分子式 | C21H29NO7 |
| 分子量 | 407.457 |
| 闪点 | 207.2ºC |
| 精确质量 | 407.194397 |
| PSA | 138.53000 |
| LogP | 0.89570 |
| 外观性状 | white |
| 蒸汽压 | 2.55E-07mmHg at 25°C |
| 储存条件 | −70℃ |
| 水溶解性 | H2O: >10mg/mL |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:5 3.氢键受体数量:8 4.可旋转化学键数量:3 5.互变异构体数量:3 6.拓扑分子极性表面积139 7.重原子数量:29 8.表面电荷:0 9.复杂度:491 10.同位素原子数量:0 11.确定原子立构中心数量:5 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:2 |
| 符号 |
GHS02, GHS06, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H225-H301 + H311 + H331-H370 |
| 警示性声明 | P210-P260-P280-P301 + P310-P311 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
| 危害码 (欧洲) | Xn |
| 风险声明 (欧洲) | R22 |
| 安全声明 (欧洲) | 7-16-36/37-45 |
| 危险品运输编码 | UN1230 - class 3 - PG 2 - Methanol, solution |
| RTECS号 | QD1930000 |
|
The role of excitatory amino acids and NMDA receptors in traumatic brain injury.
Science 244 , 798, (1989) Brain injury induced by fluid percussion in rats caused a marked elevation in extracellular glutamate and aspartate adjacent to the trauma site. This increase in excitatory amino acids was related to ... |
| (2R,3R)-2,3-Dihydroxysuccinic acid - (9α,13α,14α)-17-methylmorphinan-3-ol (1:1) |
| Levorphanol tartrate |
| 1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol tartrate,d |
| d-1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol Tartrate |
| Dextrorphan Tartrate Salt |
| 17-Methyl-morphinan-3-ol,Lg-Hydrogentartrat |
| d-3-Hydroxy-N-methylmorphinan tartrate |
| Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with (9α,13α,14α)-17-methylmorphinan-3-ol (1:1) |
| 17-methyl-morphinan-3-ol,Lg-hydrogentartrate |
| MFCD00151495 |
| (+)-(9a,13a,14a)-17-methylmorphinan-3-ol Tartrate (1:1) (Salt) |
| Dextrophan tartrate |
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