二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲结构式
|
常用名 | 二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲 | 英文名 | DPC |
---|---|---|---|---|
CAS号 | 1382469-39-7 | 分子量 | 353.48 | |
密度 | 1.2±0.1 g/cm3 | 沸点 | 510.7±48.0 °C at 760 mmHg | |
分子式 | C19H23N5S | 熔点 | N/A | |
MSDS | 美版 | 闪点 | 262.7±29.6 °C | |
符号 |
GHS06 |
信号词 | Danger |
二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲用途DpC is an anti-tumor agent. DpC inhibits cancer cell proliferation (IC50: 0.007-0.096 渭M). DpC synergizes with multiple anti-cancer therapeutics[1]. |
中文名 | 二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲 |
---|---|
英文名 | DPC |
英文别名 | 更多 |
描述 | DpC是一种抗肿瘤药物。DpC抑制癌症细胞增殖(IC50:0.007-0.096渭M) 。DpC与多种抗癌疗法协同作用[1]。 |
---|---|
相关类别 | |
参考文献 |
密度 | 1.2±0.1 g/cm3 |
---|---|
沸点 | 510.7±48.0 °C at 760 mmHg |
分子式 | C19H23N5S |
分子量 | 353.48 |
闪点 | 262.7±29.6 °C |
精确质量 | 353.167419 |
LogP | 3.27 |
外观性状 | 固体 |
蒸汽压 | 0.0±1.3 mmHg at 25°C |
折射率 | 1.649 |
储存条件 | 20°C |
符号 |
GHS06 |
---|---|
信号词 | Danger |
危害声明 | H301 |
警示性声明 | P301 + P310 |
危害码 (欧洲) | T |
危险品运输编码 | UN 2811 6.1 / PGIII |
The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.
Oncotarget 6 , 8851-74, (2015) N-myc downstream regulated gene-1 (NDRG1) is a potent metastasis suppressor that plays a key role in regulating signaling pathways involved in mediating cancer cell invasion and migration, including t... |
|
The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
J. Biol. Chem. 291 , 1029-52, (2016) N-MYC downstream-regulated gene-1 (NDRG1) is a potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of cellular signaling pathways, including the TGF-β pa... |
DI-2-PYRIDYLKETONE 4-CYCLOHEXYL-4-METHYL-3-THIOSEMICARBAZONE |
N-Cyclohexyl-2-(di-2-pyridinylmethylene)-N-methylhydrazinecarbothioamide |
Hydrazinecarbothioamide, N-cyclohexyl-2-(di-2-pyridinylmethylene)-N-methyl- |
DPC |
Di-2-pyridylketone-4-cyclohexyl-4-methyl-3-thiosemicarbazone |
MFCD22666593 |