7041-61-4

• 常用中文名：Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate
• 常用英文名：Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate
• CAS号：7041-61-4
• 分子式：C₁₅H₁₇N₃O₆
• 分子量：335.31200
• 发布时间：2016-02-03 07:01:18
• 更新时间：2024-01-15 17:25:10

名称

• 英文名: Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate
• 英文别名: 7-demethylmitomycin A; N-[2-(7-hydroxy-naphthalen-1-yl)ethyl]acetamide; N-[2-(7-hydroxy-naphth-1-yl)ethyl]acetamide; 7-Demethyl-Agomelatine; 7-hydroxymitosane; 7-hydroxy-9a-methoxymitosane; N-[2-(7-Hydroxy-1-naphthyl)ethyl]-acetamide

物化性质

• 密度: 1.61g/cm3
• 沸点: 512.1ºC at 760 mmHg
• 分子式: C₁₅H₁₇N₃O₆
• 分子量: 335.31200
• 闪点: 263.5ºC
• 精确质量: 335.11200
• PSA: 141.10000
• 折射率: 1.683

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CN0880000 CAS REGISTRY NUMBER : 7041-61-4 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C15-H17-N3-O6 MOLECULAR WEIGHT : 335.35 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 20,72,1967

合成路线

50-07-7 ~84% 7041-61-4

文献：Grueschow, Sabine; Chang, Leng-Chee; Mao, Yingqing; Sherman, David H. Journal of the American Chemical Society, 2007 , vol. 129, # 20 p. 6470 - 6476

4055-39-4 ~% 7041-61-4

文献：Beijnen; Van der Houwen; Rosing; Underberg Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2900 - 2913

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