263149-10-6

• 常用中文名：4-氯-7-羟基-6-甲氧-3-腈基喹啉
• 常用英文名：4-Chlor-7-hydroxy-6-methoxychinolin-3-carbonitril
• CAS号：263149-10-6
• 分子式：C₁₁H₇ClN₂O₂
• 分子量：234.639
• 相关类别： 医药中间体 杂环化合物 喹啉类化合物
• 发布时间：2019-01-29 16:50:35
• 更新时间：2024-01-02 13:57:05

名称

• 中文名: 4-氯-7-羟基-6-甲氧基喹啉-3-甲腈
• 英文名: 4-chloro-6-methoxy-7-oxo-1H-quinoline-3-carbonitrile
• 中文别名: 4-氯-3-氰基-7-羟基-6-甲氧基喹啉
• 英文别名: 4-chloro-3-cyano-7-hydroxy-6-methoxyquinoline; 4-Chlor-7-hydroxy-6-methoxychinolin-3-carbonitril; QC-1109; 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile; 4-Chloro-7-hydroxy-6-methoxy-3-quinolinecarbonitrile; 3-Quinolinecarbonitrile, 4-chloro-7-hydroxy-6-methoxy-; 4-chloro-7-hydroxy-6-methoxyquinoline-3-carbonitrile

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 439.0±40.0 °C at 760 mmHg
• 分子式: C₁₁H₇ClN₂O₂
• 分子量: 234.639
• 闪点: 219.3±27.3 °C
• 精确质量: 234.019608
• PSA: 66.14000
• LogP: 2.01
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.677
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933499090

合成路线

214476-99-0 ~99% 263149-10-6

文献：AstraZeneca AB Patent: EP1584619 A1, 2005 ; Location in patent: Page/Page column 41-42 ; EP 1584619 A1

741276-43-7 ~% 263149-10-6

文献：Cao, Xin; You, Qi-Dong; Li, Zhi-Yu; Liu, Xiao-Rong; Xu, Dan; Guo, Qing-Long; Shang, Jing; Chern, Ji-Wang; Chen, Meng-Ling Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 23 p. 6206 - 6209

3943-74-6 ~% 263149-10-6

文献：Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480

3535-27-1 ~% 263149-10-6

文献：Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480

50413-53-1 ~% 263149-10-6

文献：Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480

948553-02-4 ~% 263149-10-6

文献：Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480

319492-96-1 ~% 263149-10-6

文献：Wang, Yanong D.; Miller, Karen; Boschelli, Diane H.; Ye, Fei; Wu, Biqi; Floyd; Powell, Dennis W.; Wissner, Allan; Weber, Jennifer M.; Boschelli, Frank Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 21 p. 2477 - 2480

上下游产品

上游产品  7
214476-99-0 741276-43-7 3943-74-6 3535-27-1
50413-53-1 948553-02-4 319492-96-1
下游产品  5
214470-72-1 214470-55-0 214470-68-5 214475-98-6
380844-38-2

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%