159991-07-8

• 常用中文名：(4aS,7aS)-八氢-1H-吡咯并[3,4-b]吡啶-1-羧酸叔丁酯
• 常用英文名：tert-butyl (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate
• CAS号：159991-07-8
• 分子式：C₁₂H₂₂N₂O₂
• 分子量：226.315
• 发布时间：2018-06-17 12:07:15
• 更新时间：2024-01-15 10:22:01

名称

• 中文名: 八氢吡咯并[3.4-b]吡啶-1-羧酸叔丁酯
• 英文名: tert-butyl (4aS,7aS)-2,3,4,4a,5,6,7,7a-octahydropyrrolo[3,4-b]pyridine-1-carboxylate
• 英文别名: (4AS,7AS)-TERT-BUTYL OCTAHYDROPYRROLO[3,4-B]PYRIDINE-1-CARBOXYLATE; tert-butyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate; 2-Methyl-2-propanyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate; cis-octahydro-pyrrolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; (4aS,7aS)-1-t-Butoxycarbonyloctahydropyrrolo[3.4-b]pyridine; (S,S)-8-tertiary-butyloxycarbonyl-2,8-diazabicyclo(4.3.0)nonane; (4aS,7aS)-tert-Butyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate; (S,S)-2-tert-butoxycarbonyl-2,8-diazabicyclo[4.3.0]nonan; [1S,6S]-2-tertbutyloxycarbonyl-2,8-diazabicyclo[4.3.0]nonane; 1H-Pyrrolo[3,4-b]pyridine-1-carboxylic acid, octahydro-, 1,1-dimethylethyl ester; tert-Butyl cis-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 313.8±15.0 °C at 760 mmHg
• 分子式: C₁₂H₂₂N₂O₂
• 分子量: 226.315
• 闪点: 143.6±20.4 °C
• 精确质量: 226.168121
• PSA: 41.57000
• LogP: 1.06
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.489
• 储存条件: 2-8°C，避光，保存于惰性气体中

合成路线

159991-06-7 ~87% 159991-07-8

文献：Institute of Medicinal Biotechnology, Chinese Acadamy of Medical Sciences; Zhe Jiang Medecine Co., Ltd. Xinchang Pharmaceutical Factory Patent: EP1767536 A1, 2007 ; Location in patent: Page/Page column 10 ;

151213-39-7 24424-99-5 ~% 159991-07-8

文献：ABBOTT LABORATORIES Patent: US2011/230459 A1, 2011 ;