345264-02-0

• 常用中文名：2-(5,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-基)-2-氧代乙酸甲酯
• 常用英文名：Methyl 2-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-2-Oxoacetate
• CAS号：345264-02-0
• 分子式：C₁₄H₁₃NO₃
• 分子量：243.25800
• 发布时间：2017-07-26 11:44:32
• 更新时间：2024-01-09 14:47:04

名称

• 中文名: 2-(5,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-基)-2-氧代乙酸甲酯
• 英文名: Methyl 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl(oxo)acetate
• 英文别名: (5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-oxo-acetic acid methyl ester; (5,6-dihydro-4H-pyrrolo-[3,2,1-ij]-quinolin-1-yl)-carboxylic acid; methyl 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl-oxoacetate; 2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl ester

物化性质

• 分子式: C₁₄H₁₃NO₃
• 分子量: 243.25800
• 精确质量: 243.09000
• PSA: 48.30000
• LogP: 1.94320
• 储存条件: 室温

合成路线

5840-01-7 124-41-4 ~86% 345264-02-0

文献：ARQULE, INC. Patent: WO2006/86484 A1, 2006 ; Location in patent: Page/Page column 52-53 ;

67-56-1 5840-01-7 79-37-8 124-41-4 ~92% 详细

文献：ArQule, Inc. Patent: US2012/165278 A1, 2012 ; Location in patent: Page/Page column 29-30 ;

5840-01-7 79-37-8 124-41-4 ~84% 345264-02-0

文献：Al-Awar, Rima Salim; Hecker, Kyle Andrew; Ray, James Edward; Huang, Jianping; Joseph, Sajan; Li, Tiechao; Paal, Michael; Rathnachalam, Radhakrishnan; Shih, Chuan; Waid, Philip Parker; Zhou, Xun; Zhu, Guoxin Patent: US2003/229026 A1, 2003 ; Location in patent: Page 15 ; US 20030229026 A1

67-56-1 5840-01-7 79-37-8 ~% 345264-02-0

文献：ARQULE, INC.; Nakamura, Yoshitaka; Ooyama, Jo Patent: US2013/281699 A1, 2013 ; Location in patent: Paragraph 0123; 0124 ;

67-56-1 124-41-4 ~% 345264-02-0

文献：ELI LILLY AND COMPANY Patent: WO2003/76442 A1, 2003 ; Location in patent: Page/Page column 40-41 ; WO 03/076442 A1

5840-01-7 ~% 345264-02-0

文献：Al-Awar, Rima S.; Ray, James E.; Hecker, Kyle A.; Huang, Jianping; Waid, Philip P.; Shih, Chuan; Brooks, Harold B.; Spencer, Charles D.; Watkins, Scott A.; Patel, Bharvin R.; Stamm, Nancy B.; Ogg, Catherine A.; Schultz, Richard M.; Considine, Eileen L.; Faul, Margaret M.; Sullivan, Kevin A.; Kolis, Stanley P.; Grutsch, John L.; Joseph, Sajan Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3217 - 3220

上下游产品

上游产品  4
5840-01-7 124-41-4 67-56-1 79-37-8
下游产品  2
905854-02-6 345261-20-3