| 中文名 | 2-苯基-4-羟甲基噻唑 |
|---|---|
| 英文名 | (2-phenyl-1,3-thiazol-4-yl)methanol |
| 英文别名 |
2-phenyl-4-thiazolylmethanol
2-phenyl-4-hydroxymethylthiazole 2-Phenyl-4-hydroxymethyl-thiazol 4-Thiazolemethanol,2-phenyl (2-phenyl-thiazol-4-yl)-methanol 4-hydroxymethyl-2-phenylthiazole 4-(Hydroxymethyl)-2-phenyl-1,3-thiazole |
| 密度 | 1.264g/cm3 |
|---|---|
| 沸点 | 372.2ºC at 760mmHg |
| 熔点 | 65ºC |
| 分子式 | C10H9NOS |
| 分子量 | 191.25000 |
| 闪点 | 178.9ºC |
| 精确质量 | 191.04000 |
| PSA | 61.36000 |
| LogP | 2.30240 |
| 蒸汽压 | 3.37E-06mmHg at 25°C |
| 折射率 | 1.629 |
| 储存条件 | 2-8°C |
Synonym:2-Phenyl-hydroxymethyl thiazol Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 24/25 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Toxic in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 23780-13-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: cream Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 67 - 70 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H9NOS Molecular Weight: 191 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, bases, acid chlorides. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 23780-13-4 unlisted. LD50/LC50: Not available. Carcinogenicity: (2-Phenyl-1,3-thiazol-4-yl)methanol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: R 24/25 Toxic in contact with skin and if swallowed. Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 23780-13-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 23780-13-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 23780-13-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi: Irritant; |
|---|---|
| 风险声明 (欧洲) | R24/25 |
| 安全声明 (欧洲) | 22-36/37/39 |
| 海关编码 | 2934100090 |
|
~74%
23780-13-4 |
| 文献：BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ; Location in patent: Paragraph 00145 ; |
|
~%
23780-13-4 |
| 文献：EP1228067 B1, ; Page 67 ; |
|
~94%
23780-13-4 |
| 文献：Kwon, Il-Chun; Koh, Young Kook; Choi, Jun-Hyeak; Kim, Hong-Seok Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1883 - 1886 |
|
~%
23780-13-4 |
| 文献：Journal of the American Chemical Society, , vol. 65, p. 1667,1669 |
|
~%
23780-13-4 |
| 文献：Journal of the American Chemical Society, , vol. 65, p. 1667,1669 |
|
~62%
23780-13-4 |
| 文献：Orr, David; Tolfrey, Alexandra; Percy, Jonathan M.; Frieman, Joanna; Harrison, Zoe A.; Campbell-Crawford, Matthew; Patel, Vipulkumar K. Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9655 - 9662 |
|
~%
23780-13-4 |
| 文献：Archiv der Pharmazie, , vol. 343, # 7 p. 411 - 416 |
| 上游产品 7 | |
|---|---|
| 下游产品 3 | |
| 海关编码 | 2934100090 |
|---|---|
| 中文概述 | 2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
