112290-21-8

• 常用中文名：2-(4-Chlorophenoxyacetylamino)-3-ethoxycarbonylthieno(2,3-b)quinuclidi ne
• 常用英文名：2-(4-Chlorophenoxyacetylamino)-3-ethoxycarbonylthieno(2,3-b)quinuclidi ne
• CAS号：112290-21-8
• 分子式：C₂₀H₂₁ClN₂O₄S
• 分子量：420.91000
• 发布时间：2017-08-05 15:30:15
• 更新时间：2024-01-02 08:48:40

名称

• 英文名: 2-(4-Chlorophenoxyacetylamino)-3-ethoxycarbonyl<2,3-b>quinuclidine

物化性质

• 密度: 1.42g/cm3
• 沸点: 636ºC at 760mmHg
• 分子式: C₂₀H₂₁ClN₂O₄S
• 分子量: 420.91000
• 闪点: 338.4ºC
• 精确质量: 420.09100
• PSA: 99.60000
• LogP: 5.00760
• 蒸汽压: 4.48E-16mmHg at 25°C
• 折射率: 1.648

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KM5847900 CHEMICAL NAME : 4H-4,7-Ethanothieno(2,3-b)pyridine-3-carboxylic acid, 5,6-dihydro-2-(((4-chlorophenoxy)acetyl)amino)-, ethyl ester CAS REGISTRY NUMBER : 112290-21-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H21-Cl-N2-O4-S MOLECULAR WEIGHT : 420.94 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 21,568,1987

合成路线

4122-68-3 36860-49-8 ~85% 112290-21-8

文献：Kaminka, M. E.; Vorob'eva, V. Ya.; Nikitin, V. B.; Mikhlina, E. E.; Zhirnikova, M. L.; Yakhontov, L. N. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 8 p. 568 - 570 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 8 p. 945 - 948

3731-38-2 ~% 112290-21-8

文献：Kaminka, M. E.; Vorob'eva, V. Ya.; Nikitin, V. B.; Mikhlina, E. E.; Zhirnikova, M. L.; Yakhontov, L. N. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 8 p. 568 - 570 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 8 p. 945 - 948

105-56-6 ~% 112290-21-8

文献：Kaminka, M. E.; Vorob'eva, V. Ya.; Nikitin, V. B.; Mikhlina, E. E.; Zhirnikova, M. L.; Yakhontov, L. N. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 8 p. 568 - 570 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 8 p. 945 - 948